Can Splenda Help Reduce Cancer Risk? 


Sponsored by Splenda.


In the realm of sugar substitutes, there is no brand as well-known as Splenda. Marketed as a calorie-free alternative to sugar, Splenda has helped consumers reduce their added sugar intake and reach their health goals for 25 years. And over the years one thing has remained clear: Splenda, with its key component, sucralose, has been extensively studied and proven to be safe for consumption.

Debunking the Sucralose Myths

Is Sucralose Harmful? 

One of the most pervasive myths surrounding Splenda is its supposed harmful effects on human health. Contrary to popular belief, numerous studies have demonstrated the safety of sucralose, the primary ingredient in Splenda. Additionally, Research spanning decades has consistently shown no evidence linking sucralose consumption to an increased risk of cancer or any other serious health issues1.

Dispelling Health Risks and DNA Damage Claims

It appears social media is flooded with influencers demonizing diet sodas and other products made with non-nutritive sweeteners. In reality, Claims suggesting sucralose poses risks to human health or causes DNA damage have been thoroughly investigated and debunked. Furthermore, regulatory agencies such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA) have rigorously evaluated the safety of sucralose and deemed it safe for consumption2-3.

Reducing Cancer Risk: How Sucralose Supports a Healthier Lifestyle

In the pursuit of cancer prevention, maintaining a balanced diet plays a pivotal role. Surprisingly, incorporating sucralose, the key component in Splenda, into one’s diet could offer more than just a sweet taste—it might also contribute to cancer risk reduction by aiding in calorie management to aid in lowering or managing body fat tissue.

Sucralose: A Sweet Solution with Calorie Control

Sucralose presents a unique opportunity to sweeten foods and beverages without adding extra calories. Its sweetness allows individuals to indulge in sweet treats without worrying about the calorie load. Therefore, by substituting sugar with sucralose, one can effectively reduce their overall calorie intake. This may, as a result, lead to a decrease in fat tissue accumulation, helping to reduce the risk of 13 different cancers.

There is strong evidence that having excess fat tissue is a cause of at least 13 different types of cancer 4-5:

  • Bowel cancer
  • Breast cancer (post-menopausal)
  • Gallbladder cancer
  • Kidney cancer
  • Liver cancer
  • Mouth, pharynx and larynx cancer
  • Oesophageal cancer (adenocarcinoma)
  • Ovarian cancer
  • Pancreatic cancer
  • Prostate cancer (advanced)
  • Stomach cancer (cardia)
  • Endometrial or uterine cancer

Being a healthy weight can also help to reduce your risk of heart disease and type 2 diabetes6.

The Safest Sweetener on the Block

Without a doubt, Splenda continually stands out as one of the safest sweeteners available. With its zero-calorie nature and zero impact on blood sugar levels, it offers a viable option for individuals looking to manage their weight or control their sugar intake. Additionally, its stability under high temperatures makes it suitable for various culinary applications, from baking to beverages. Splenda retains its sweetness and does not degrade or lose its properties when cooked at normal baking temperatures.

In baking, where temperatures can reach up to 350°F to 375°F (175°C to 190°C), Splenda can also be used as a substitute for sugar without any significant issues. It’s even suitable for cooking processes like caramelization, since it can withstand the heat without breaking down or losing its sweetness. So you can make those sweet treats without losing any sweetness and still lower your calorie intakes for your weight management goals, win win!

Sucralose: A Tool for Healthier Living

Incorporating Splenda into one’s dietary regimen can serve as a practical approach to managing calorie intake and, consequently, reducing fat tissue. By replacing sugar with sucralose  in recipes and beverages, individuals can enjoy the sweetness they crave while potentially mitigating their risk of cancer. Moreover, the absence of calories in sucralose makes it an appealing option for those striving to maintain a healthy weight and lifestyle to reduce the risk of several cancers.

Furthermore, Splenda products have been safely used by millions of people worldwide since 1991, as affirmed by the highest-regarded international and government regulatory agencies. These agencies unquestionably affirm that low- and no-calorie sweeteners like Splenda are completely safe for consumption.

Low- and no-calorie sweeteners like Splenda also play an important role in the fight against the epidemics of obesity and diabetes. Major health organizations agree that these sweeteners can be a helpful tool for reducing calorie and added sugar intake, aiding in weight and diabetes management.

Embracing Versatility: Recipes with Splenda

1. Baked Banana Bread with Splenda


  • 1 ¾ cups all-purpose flour
  • 1 teaspoon baking soda
  • ½ teaspoon salt
  • ½ cup unsalted butter, softened
  • 1 cup mashed ripe bananas (about 2 medium bananas)
  • ¾ cup Splenda
  • 2 eggs
  • 1 teaspoon vanilla extract
  • ½ cup chopped walnuts (optional)


  • Preheat the oven to 350°F (175°C) and grease a 9×5-inch loaf pan.
  • In a medium bowl, combine flour, baking soda, and salt. Set aside.
  • In a separate bowl, cream together butter and Splenda until light and fluffy. Beat in eggs one at a time, then stir in mashed bananas and vanilla extract.
  • Gradually add the flour mixture to the banana mixture, stirring until just combined. Fold in chopped walnuts, if using.
  • Pour the batter into the prepared loaf pan and smooth the top.
  • Bake for 60-65 minutes, or until a toothpick inserted into the center comes out clean. Allow the bread to cool in the pan for 10 minutes before transferring to a wire rack to cool completely.

2. Fresh Lavender and Lemonade with Splenda


  • 1 cup freshly squeezed lemon juice
  • ½ cup Splenda
  • 4 cups water
  • 2-3 sprigs fresh lavender (optional)
  • Ice cubes
  • Lemon slices for garnish


  • In a pitcher, combine lemon juice, Splenda, and water. Stir until Splenda is dissolved.
  • Add fresh lavender sprigs to the pitcher, if desired, and refrigerate for at least 1 hour to allow the flavors to infuse.
  • Before serving, remove lavender sprigs and stir the lemonade. Fill glasses with ice cubes and pour the lemonade over the ice.
  • Garnish with lemon slices and additional lavender sprigs, if desired.

3. Blueberry Muffins with Splenda


  • 1 ¾ cups all-purpose flour
  • ½ cup Splenda
  • 2 teaspoons baking powder
  • ½ teaspoon salt
  • ¾ cup milk
  • ⅓ cup vegetable oil
  • 1 egg
  • 1 cup fresh or frozen blueberries


  • Preheat the oven to 400°F (200°C) and grease or line a muffin tin.
  • In a large bowl, combine flour, Splenda, baking powder, and salt.
  • In another bowl, whisk together milk, vegetable oil, and egg.
  • Add the wet ingredients to the dry ingredients and stir until just combined. Fold in the blueberries.
  • Spoon the batter into the prepared muffin tin, filling each cup about 2/3 full.
  • Bake for 18-20 minutes, or until a toothpick inserted into the center comes out clean. Remove from the oven and allow the muffins to cool in the tin for a few minutes before transferring to a wire rack to cool completely.

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Are you a cancer survivor in treatment?…picture this: you are leaving your oncology appointment and despite the million questions swirling in your mind, you got a handout . . . yay . . . although it has some great information, it doesn’t really scratch the surface when it comes to navigating nutrition during cancer. That’s why I made my self paced Masterclass course: The Power of Nutrition – to boil down the basics so that you can feel confident about nourishing yourself and supporting your health RIGHT NOW during your treatment. Fall in love with food again without consulting Dr. Google before each bite. Consider this your ticket to healing, gaining muscle, immunity AND energy.


  1. Ashwell M, Gibson S, Bellisle F, et al. Expert consensus on low-calorie sweeteners: facts, research gaps and suggested actions. Nutr Res Rev. 2020;33(1):145-154. doi:10.1017/S0954422419000283
  2. Roberts A. The safety and regulatory process for low calorie sweeteners in the United States. Physiol Behav. 2016;164(Pt B):439-444. doi:10.1016/j.physbeh.2016.02.039
  3. Magnuson BA, Roberts A, Nestmann ER. Critical review of the current literature on the safety of sucralose. Food Chem Toxicol. 2017;106(Pt A):324-355. doi:10.1016/j.fct.2017.05.047
  4. Warshaw H, Edelman SV. Practical Strategies to Help Reduce Added Sugars Consumption to Support Glycemic and Weight Management Goals. Clin Diabetes. 2021;39(1):45-56. doi:10.2337/cd20-0034
  5. World Cancer Research Fund/American Institute for Cancer Research. (2018). Diet, Nutrition, Physical Activity and Cancer: a Global Perspective. Continuous Update Project Expert Report. Available at
  6. Wing, R. R., & Hill, J. O. (2001). Successful weight loss maintenance. New England Journal of Medicine, 341(21), 1561-1568.

This blog is not intended as medical nutrition therapy, medical advice, or diagnosis and should in no way replace consultation or recommendation from your medical professional.

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